(A) Schematic of the in vivo loading experiment. (2021), "MicroFE models of porcine vertebrae with induced bone focal lesions: Validation of predicted displacements with digital volume correlation", Journal of the Mechanical Behavior of Biomedical Materials, URL: The Role of the Loading Condition in Predictions of Bone Adaptation in a Mouse Tibial Loading Model More complex models instead are required to predict regions with high deformation. In conclusion, these simplified models can predict how close to failure a bone is.
By contrast, poor correlation was found in the closeness of the growth plates. The comparison between the predicted displacements and the measured displacements showed an excellent agreement in the middle portion of the vertebral body, both with and without lesions. Simplified linear microFE models of the vertebrae, based on microCT images, were developed.īoundary conditions were imposed from DVC data, and the displacement field was predicted. In this study, porcine vertebrae (with and without artificial lesions) were mechanically tested within a microCT scanner, and the displacement field was measured though a global Digital Volume Correlation approach. Micro Finite Element models have the potential of predicting the mechanical behavior of vertebrae with metastatic lesions at tissue level through laboratory studies, but their predictions must be validated against experimental measurements. (2021), "MicroFE models of porcine vertebrae with induced bone focal lesions: Validation of predicted displacements with digital volume correlation", JMBBM Image Abstract for Palanca, M., Oliviero, S., Dall'Ara, E. Conferences, events, visitor accommodation and weddings.Worldwide Universities Network at Sheffield.Research centres, institutes and networks.
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